Journal of Minimal Access Surgery

SYSTEMATIC REVIEW
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Year : 2022  |  Volume : 18  |  Issue : 1  |  Page : 1--11

Pure laparoscopic versus open donor hepatectomy for adult living donor liver transplantation – A systematic review and meta-analysis

Michail Papoulas1, Abdul Rahman Hakeem2, Nigel Heaton1, Krishna V Menon1 
1 Department of Institute of Liver Studies, Institute of Liver Studies, King's College Hospital, Denmark Hill, London, UK
2 Department of Hepatobiliary and Liver Transplantation, St. James's University Hospital NHS Trust, Leeds, UK

Correspondence Address:
Mr. Krishna V Menon
Institute of Liver Studies, King's College Hospital, Denmark Hill, London, SE5 9RS
UK

Background: Pure laparoscopic donor hepatectomy (PLDH) for adult living donor liver transplantation (LDLT) remains controversial. The aim of this study was to undertake a systematic review and meta-analysis of donor outcomes following PLDH for adult LDLT. Materials and Methods: Systematic review in line with the meta-analysis of observational studies in epidemiology guidelines. Results: Eight studies were included in the systematic review and six in the meta-analysis. A total of 575 donors underwent PLDH for adult LDLT. The mean donor age was 32.8 years with a BMI of 23.4 kg/m2 and graft weight of 675 g. The mean operative time was 353 min and the conversion rate was 2.8% (n = 16). Overall morbidity was 10.8% with 1.6% major complications (Clavien-Dindo grade 3b), zero mortality and 9.0 days length of stay (LOS). The meta-analysis demonstrated that the operative time was significantly shorter for the open donor hepatectomy group (mean difference 29.15 min; P = 0.006) and the LOS was shorter for the PLDH group (mean difference −0.73 days; P = 0.02), with a trend towards lesser estimated blood loss in PLDH group. However, no difference between the two groups was noted in terms of overall morbidity or major complications. Conclusions: Perioperative outcomes of PLDH are similar to the standard open approach in highly specialised centers with trend towards lesser blood loss and overall shorter hospital stay. Careful donor selection and standardisation of the technique are imperative for the successful implementation and adoption of the procedure worldwide.


How to cite this article:
Papoulas M, Hakeem AR, Heaton N, Menon KV. Pure laparoscopic versus open donor hepatectomy for adult living donor liver transplantation – A systematic review and meta-analysis.J Min Access Surg 2022;18:1-11


How to cite this URL:
Papoulas M, Hakeem AR, Heaton N, Menon KV. Pure laparoscopic versus open donor hepatectomy for adult living donor liver transplantation – A systematic review and meta-analysis. J Min Access Surg [serial online] 2022 [cited 2022 Jan 27 ];18:1-11
Available from: https://www.journalofmas.com/article.asp?issn=0972-9941;year=2022;volume=18;issue=1;spage=1;epage=11;aulast=Papoulas;type=0